Biosynthetic Studies and Genetic Engineering of Pactamycin Analogs with Improved Selectivity toward Malarial Parasites

Radical SAM, a novel protein superfamily linking unresolved steps in familiar biosynthetic pathways with radical mechanisms: functional characterization using new analysis and information visualization methods

Heidi J. Sofia · Nucleic Acids Research · 2001 · 1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

The Structural Basis for the Action of the Antibiotics Tetracycline, Pactamycin, and Hygromycin B on the 30S Ribosomal Subunit

Ditlev E. Brodersen, William Clemons, Andrew P. Carter et al. · Cell · 2000 · 940 citations · Full text

Life Sciences, Microbiology, Molecular Biology +17

Molecular characterization and analysis of the biosynthetic gene cluster for the antitumor antibiotic mitomycin C from Streptomyces lavendulae NRRL 2564

Yingqing Mao, Mustafa Varoglu, David H. Sherman · Chemistry & Biology · 1999 · 174 citations · Full text

Life Sciences, Microbiology, Molecular Biology +15

Dissecting the Ribosomal Inhibition Mechanisms of Edeine and Pactamycin

George P. Dinos, Daniel N. Wilson, Yoshika Teraoka et al. · Molecular Cell · 2004 · 159 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

Effect of Pactamycin on Synthesis of Poliovirus Proteins: a Method for Genetic Mapping

Robert Taber, David Rekosh, David Baltimore · Journal of Virology · 1971 · 128 citations · Full text

Life Sciences, Genetics, Molecular Biology +16