Agonist potency determination by patch clamp analysis of single glutamate receptors

Single acetylcholine-activated channels show burst-kinetics in presence of desensitizing concentrations of agonist

Bert Sakmann, Joseph B. Patlak, Erwin Neher · Nature · 1980 · 605 citations

Life Sciences, Neuroscience, Pharmacology +12

The extracellular patch clamp: A method for resolving currents through individual open channels in biological membranes

Erwin Neher, Bert Sakmann, Joe Henry Steinbach · Pflügers Archiv - European Journal of Physiology · 1978 · 517 citations · Full text

Natural Sciences, Biophysics, Cell Biology +16

Single glutamate-activated channels in locust muscle

Joseph B. Patlak, K.A.F. Gration, P.N.R. Usherwood · Nature · 1979 · 178 citations

Life Sciences, Neuroscience, Physiology +11

Concanavalin A blocks desensitisation of glutamate receptors on insect muscle fibres

D A Mathers, P.N.R. Usherwood · Nature · 1976 · 156 citations

Life Sciences, Neuroscience, Pharmacology +8

Glutamate current noise: post‐synaptic channel kinetics investigated under voltage clamp.

C. R. Anderson, Stuart Cull-Candy, Ricardo Miledi · The Journal of Physiology · 1978 · 103 citations

Natural Sciences, Biophysics, Neuroscience +17