Evaluation of chitosan salts as non-viral gene vectors in CHO-K1 cells

Chitosan and depolymerized chitosan oligomers as condensing carriers for in vivo plasmid delivery

Fiona MacLaughlin, Russell J. Mumper, Jijun Wang et al. · Journal of Controlled Release · 1998 · 599 citations

Pharmacy, Pharmaceutical Biotechnology, Pharmaceutics +14

Chitosan as a nonviral gene delivery system. Structure–property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo

Magnus Köping‐Höggård, Ioannis Tubulekas, Haitao Guan et al. · Gene Therapy · 2001 · 529 citations

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +15

Potential of low molecular mass chitosan as a DNA delivery system: biocompatibility, body distribution and ability to complex and protect DNA

Simon C. W. Richardson · International Journal of Pharmaceutics · 1999 · 526 citations

Pharmacy, Bioengineering, Biomedical Engineering +16

High efficiency gene transfer using chitosan/DNA nanoparticles with specific combinations of molecular weight and degree of deacetylation

Marc Lavertu, Stéphane Méthot, Nicolas Tran‐Khanh et al. · Biomaterials · 2006 · 441 citations

Life Sciences, Bioengineering, Biotechnology +17

In vitro gene delivery mediated by chitosan. Effect of pH, serum, and molecular mass of chitosan on the transfection efficiency

Toshinori Sato, Tsuyoshi Ishii, Yoshio Okahata · Biomaterials · 2001 · 423 citations

Pharmacy, Biotechnology, Molecular Pharmaceutics +16