Gel microdrop technology for rapid isolation of rare and high producer cells

Antigen-specific identification and cloning of hybridomas with a fluorescence-activated cell sorter.

David R. Parks, V M Bryan, Vernon T. Oi et al. · Proceedings of the National Academy of Sciences · 1979 · 383 citations · Full text

Life Sciences, Biotechnology, Immunology +15

Loss of Antibody Productivity During Long-Term Cultivation of a Hybridoma Cell Line in Low Serum and Serum-Free Media

Sadettin S. Ozturk, Bernhard Ø. Palsson · Hybridoma · 1990 · 78 citations

Life Sciences, Cell Biology, Immunology +13

Hazards of the limiting-dilution method of cloning hybridomas

P. Anne Underwood, Penny A. Bean · Journal of Immunological Methods · 1988 · 76 citations

Life Sciences, Biology, Biotechnology +6

Gel Microdroplets and Flow Cytometry: Rapid Determination of Antibody Secretion by Individual Cells Within a Cell Population

KEVIN T. POWELL, James C. Weaver · Nature Biotechnology · 1990 · 70 citations

Life Sciences, Cell Biology, Immunology +13

Application of flow cytometric measurement of surface IgG in kinetic analysis of monoclonal antibody synthesis and secretion by murine hybridoma cells

Eliane Meilhoc, K. Dane Wittrup, James E. Bailey · Journal of Immunological Methods · 1989 · 58 citations

Life Sciences, Biochemistry, Immunology +14