HIV-infected subjects with the E4 allele for APOE have excess dementia and peripheral neuropathy

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.

Warren J. Strittmatter, Ann M. Saunders, D. E. Schmechel et al. · Proceedings of the National Academy of Sciences · 1993 · 4.3K citations · Full text

Life Sciences, Genetics, Neurology +17

Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's disease

Ann M. Saunders, Warren J. Strittmatter, D. E. Schmechel et al. · Neurology · 1993 · 3.8K citations · Full text

Life Sciences, Genetics, Neurology +17

Activation of microglial cells by β-amyloid protein and interferon-γ

Lucia Meda, Marco A. Cassatella, Györgyi I. Szendrei et al. · Nature · 1995 · 1.3K citations

Life Sciences, Immunology, Neuroscience +14

The AIDS dementia complex: II. Neuropathology

Bradford Navia, Eun‐Sook Cho, Carol K. Petito et al. · Annals of Neurology · 1986 · 1.3K citations

Medicine, Infectious Diseases, Neurology +15

Apolipoprotein E allele–specific antioxidant activity and effects on cytotoxicity by oxidative insults and β–amyloid peptides

Masaaki Miyata, Jonathan D. Smith · Nature Genetics · 1996 · 887 citations

Life Sciences, Biochemistry, Toxicology +17