Polymorphisms of CYP2C9, VKORC1, MDR1, APOE and UGT1A1 Genes and the Therapeutic Warfarin Dose in Brazilian Patients with Thrombosis: A Prospective Cohort Study

Estimation of the Warfarin Dose with Clinical and Pharmacogenetic Data

Teri E. Klein · New England Journal of Medicine · 2009 · 1.6K citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

Racial variability in the UDP-glucuronosyltransferase 1 ( <i>UGT1A1</i> ) promoter: A balanced polymorphism for regulation of bilirubin metabolism?

Ernest Beutler, Terri Gelbart, Anna Demina · Proceedings of the National Academy of Sciences · 1998 · 852 citations · Full text

Life Sciences, Genetics, Molecular Genetics +11

A polymorphism in the VKORC1 gene is associated with an interindividual variability in the dose-anticoagulant effect of warfarin

Giovanna D’Andrea, Rosa D’Ambrosio, P Perna et al. · Blood · 2004 · 695 citations · Full text

Medicine, Genetics, Pharmacology +14

Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C9 and VKORC1 Genotypes and Warfarin Dosing

J. A. Johnson, Li Gong, Michelle Whirl‐Carrillo et al. · Clinical Pharmacology & Therapeutics · 2011 · 648 citations

Medicine, Pharmacology, Pharmacotherapy +17

The largest prospective warfarin-treated cohort supports genetic forecasting

Mia Wadelius, Leslie Y. Chen, Jonatan D. Lindh et al. · Blood · 2008 · 552 citations · Full text

Life Sciences, Genetics, Pharmacology +4