Concepedia

A transforming mutation in the pleckstrin homology domain of AKT1 in cancer

John D. Carpten, Andrew L. Faber, Candice L. Horn, Gregory P. Donoho, Christiane M. Robbins, Galen Hostetter, Sophie Boguslawski, Tracy Moses, Stephanie Savage, Mark Uhlik,

Nature · 2007 · 1.3K citations · 32 references

DOI

Concepts

References

32

High Frequency of Mutations of the <i>PIK3CA</i> Gene in Human Cancers

Yardena Samuels, Zhenghe Wang, Alberto Bardelli et al. · Science · 2004 · 3.4K citations

, , +11

The Consensus Coding Sequences of Human Breast and Colorectal Cancers

Tobias Sjöblom, Siân Jones, Laura D. Wood et al. · Science · 2006 · 3.2K citations

, , +17

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

Thomas Franke, Sung‐Il Yang, Tung O. Chan et al. · Cell · 1995 · 2K citations · Full text

, , +16

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

Jerry M. Adams, A. W. Harris, Carl A. Pinkert et al. · Nature · 1985 · 1.8K citations

, , +16

Direct Regulation of the <i>Akt</i> Proto-Oncogene Product by Phosphatidylinositol-3,4-bisphosphate

T. Franke, David R. Kaplan, Lewis C. Cantley et al. · Science · 1997 · 1.5K citations

, , +17