Concepedia

Hemodynamic and Neuropathological Analysis in Rats with Aluminum Trichloride-Induced Alzheimer's Disease

Szu‐Ming Chen, Chi‐Chen Fan, Ming-Shiuan Chiue, Chi Chou, Jyh‐Horng Chen, Ruey‐Shyang Hseu

PLoS ONE · 2013 · 25 citations · 39 references

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Abstract

The results accentuate the importance of hemorheology and reinforce the specific association between hemodynamic and neuropathological changes in rats with AlCl3-induced AD. Hemorheological parameters, such as WBV and fibrinogen, and AChE-RBC were ultimately proven to be useful biomarkers of the severity and progression of AD patients. In addition, the parameters can be substituted for invasive inspection in therapeutic intervention.

References

39

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New guidelines for hemorheological laboratory techniques

Oğuz K. Başkurt, M. Boynard, G. Cokelet et al. · Clinical Hemorheology and Microcirculation · 2009 · 487 citations · Full text

Early-onset and Robust Cerebral Microvascular Accumulation of Amyloid β-Protein in Transgenic Mice Expressing Low Levels of a Vasculotropic Dutch/Iowa Mutant Form of Amyloid β-Protein Precursor

Judianne Davis, Feng Xu, Rashid Deane et al. · Journal of Biological Chemistry · 2004 · 367 citations · Full text

Relation between Aluminum Concentrations in Drinking Water and Alzheimer's Disease: An 8-year Follow-up Study

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Fibrinogen and β-Amyloid Association Alters Thrombosis and Fibrinolysis: A Possible Contributing Factor to Alzheimer's Disease

Marta Cortés‐Canteli, Justin Paul, Erin H. Norris et al. · Neuron · 2010 · 336 citations · Full text

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