Down regulation by iron of prostaglandin E2production by human synovial fibroblasts

Nitric oxide activates cyclooxygenase enzymes.

Daniela Salvemini, Thomas P. Misko, Jaime L. Masferrer et al. · Proceedings of the National Academy of Sciences · 1993 · 1.4K citations

Life Sciences, Biochemistry, Pharmacology +13

Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse

Scott G. Morham, Robert Langenbach, Charles D. Loftin et al. · Cell · 1995 · 1.1K citations · Full text

Medicine, Molecular Biology, Molecular Genetics +13

Prostaglandins as endogenous mediators of interleukin 1 production.

S L Kunkel, Stephen W. Chensue, Sem H. Phan · The Journal of Immunology · 1986 · 537 citations

Life Sciences, Immunology, Pharmacology +17

Selective neutralization of prostaglandin E2 blocks inflammation, hyperalgesia, and interleukin 6 production in vivo.

Joseph P. Portanova, Y Zhang, Graham Anderson et al. · The Journal of Experimental Medicine · 1996 · 420 citations · Full text

Medicine, Immunology, Pharmacology +17

Iron regulates nitric oxide synthase activity by controlling nuclear transcription.

Gabriele Werner‐Felmayer, Ernst R. Werner, K Grünewald et al. · The Journal of Experimental Medicine · 1994 · 413 citations · Full text

Life Sciences, Immunology, Molecular Biology +13