Concepedia

Use of signal specific receptor tyrosine kinase oncoproteins reveals that pathways downstream from Grb2 or Shc are sufficient for cell transformation and metastasis

Caroline Saucier, Vasilios Papavasiliou, Alexander F. Palazzo, Monica A. Naujokas, Richard Kremer, Morag Park

Oncogene · 2002 · 65 citations · 44 references

DOI

Concepts

References

44

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

Eve J. Lowenstein, Roger J. Daly, Andreas Batzer et al. · Cell · 1992 · 1.7K citations · Full text

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A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

Giuliana Pelicci, Luisa Lanfrancone, F Grignani et al. · Cell · 1992 · 1.3K citations

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Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

Maria Rozakis-Adcock, Jane McGlade, Geraldine Mbamalu et al. · Nature · 1992 · 993 citations

, , +15

Molecular cloning of a new transforming gene from a chemically transformed human cell line

Colin S. Cooper, Morag Park, Donald G. Blair et al. · Nature · 1984 · 991 citations

, , +11

A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

Carola Ponzetto, Alberto Bardelli, Flavio Maina et al. · Cell · 1994 · 991 citations

, , +12