Concepedia

8,8-Dimethyldihydroberberine with improved bioavailability and oral efficacy on obese and diabetic mouse models

Zhe Cheng, An-feng Chen, Fang Wu, Sheng Li, Hankun Zhang, Min Ji Gu, Yuanyuan Li, Lina Zhang, Lihong Hu, Jing-Ya Li,

Bioorganic & Medicinal Chemistry · 2010 · 68 citations · 37 references

DOI

Concepts

References

37

Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins

Weijia Kong, Jing Wei, Parveen Abidi et al. · Nature Medicine · 2004 · 1.4K citations

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Organelle isolation: functional mitochondria from mouse liver, muscle and cultured filroblasts

Christian Frezza, Sara Cipolat, Luca Scorrano · Nature Protocols · 2007 · 1.2K citations

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Berberine, a Natural Plant Product, Activates AMP-Activated Protein Kinase With Beneficial Metabolic Effects in Diabetic and Insulin-Resistant States

Yun Sok Lee, Woo S. Kim, Kang H. Kim et al. · Diabetes · 2006 · 1K citations

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Efficacy of berberine in patients with type 2 diabetes mellitus

Jun Yin, Jianping Ye · Metabolism · 2008 · 769 citations · Full text

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The Antidiabetic Drug Metformin Activates the AMP-Activated Protein Kinase Cascade via an Adenine Nucleotide-Independent Mechanism

Simon A. Hawley, Anne E. Gadalla, Grith Skytte Olsen et al. · Diabetes · 2002 · 688 citations · Full text

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