Concepedia

Posterior Vitreous Detachment Induced by Nattokinase (Subtilisin NAT): A Novel Enzyme for Pharmacologic Vitreolysis

Akiomi Takano, Akira Hirata, Kazuya Ogasawara, Nina Sagara, Yasuya Inomata, Takahiro Kawaji, Hidenobu Tanihara

Investigative Ophthalmology & Visual Science · 2006 · 47 citations · 20 references

DOI

Abstract

The results suggested that nattokinase is a useful enzyme for pharmacologic vitreolysis because of its efficacy in inducing PVD.

References

20

A novel fibrinolytic enzyme (nattokinase) in the vegetable cheese Natto; a typical and popular soybean food in the Japanese diet

Hirofumi Sumi, Hiroki Hamada, Hiroshi Tsushima et al. · Cellular and Molecular Life Sciences · 1987 · 564 citations

, , +9

Enhancement of the Fibrinolytic Activity in Plasma by Oral Administration of Nattokinase<sup>s</sup>

Hiroyuki Sumi, Hiroki Hamada, Kouichiro Nakanishi et al. · Acta Haematologica · 1990 · 305 citations

, , +17

The Profibrinolytic Enzyme Subtilisin NAT Purified fromBacillus subtilis Cleaves and Inactivates Plasminogen Activator Inhibitor Type 1

Tetsumei Urano, Hayato Ihara, Kazuo Umemura et al. · Journal of Biological Chemistry · 2001 · 161 citations · Full text

, , +12

Pharmacologic Induction of Posterior Vitreous Detachment in the Rabbit

Thierry Verstraeten · Archives of Ophthalmology · 1993 · 150 citations

Plasmin enzyme-assisted vitrectomy in traumatic pediatric macular holes

Alan Margherio · Ophthalmology · 1998 · 147 citations

, , +4