Concepedia

ASB16165, a phosphodiesterase 7A inhibitor, reduces cutaneous TNF-α level and ameliorates skin edema in phorbol ester 12-O-tetradecanoylphorbol-13-acetate-induced skin inflammation model in mice

Kumiko Kadoshima-Yamaoka, Megumi Goto, Masao Murakawa, Ryosuke Yoshioka, Yoshitaka Tanaka, Hidekazu Inoue, Hidenobu Murafuji, Satomi Kanki, Yasuhiro Hayashi, Kazuhiro Nagahira,

European Journal of Pharmacology · 2009 · 21 citations · 20 references

DOI

Concepts

References

20

Human keratinocytes are a source for tumor necrosis factor alpha: evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light.

A Köck, Thomas Schwarz, Reinhard Kirnbauer et al. · The Journal of Experimental Medicine · 1990 · 709 citations · Full text

, , +13

Cellular localization of interleukin-8 and its inducer, tumor necrosis factor-alpha in psoriasis.

B J Nickoloff, Gerald D. Karabin, Juliet N. Barker et al. · PubMed · 1991 · 435 citations

, , +14

Human keratinocytes contain mRNA indistinguishable from monocyte interleukin 1 alpha and beta mRNA. Keratinocyte epidermal cell-derived thymocyte-activating factor is identical to interleukin 1.

Thomas S. Kupper, Dean W. Ballard, A O Chua et al. · The Journal of Experimental Medicine · 1986 · 386 citations · Full text

, , +12

CD3- and CD28-Dependent Induction of PDE7 Required for T Cell Activation

Linsong Li, Cassian Yee, Joseph A. Beavo · Science · 1999 · 256 citations

, , +15

Isolation and characterization of a previously undetected human cAMP phosphodiesterase by complementation of cAMP phosphodiesterase-deficient Saccharomyces cerevisiae

Tamar Michaeli, Timothy J. Bloom, Timothy J. Martins et al. · Journal of Biological Chemistry · 1993 · 228 citations · Full text

, , +9