Concepedia

The GLU298ASP variant of nitric oxide synthase interacts with asymmetric dimethyl arginine in determining cardiovascular mortality in patients with end-stage renal disease

A. Testa, Belinda Spoto, Giovanni Tripepi, Francesca Mallamaci, Lorenzo Malatino, Pasquale Fatuzzo, Renke Maas, Rainer Boeger, Carmine Zoccali

Journal of Hypertension · 2005 · 31 citations · 33 references

Abstract

The T allele of the Glu298Asp polymorphism predicts cardiovascular mortality and interacts with plasma ADMA in determining this outcome in dialysis patients.

References

33

A simple salting out procedure for extracting DNA from human nucleated cells

S.A. Miller, Dale D. Dykes, Herbert F. Polesky · Nucleic Acids Research · 1988 · 20.4K citations · Full text

Chromatin, Dna Sequencing, Molecular Biological Method +11

Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure

A. Leone, S. Moncada, Patrick Vallance et al. · The Lancet · 1992 · 2.1K citations

Urology, Renal Function, Chronic Renal Failure +13

Plasma concentration of asymmetrical dimethylarginine and mortality in patients with end-stage renal disease: a prospective study

Carmine Zoccali, Stefanie M. Bode‐Böger, Francesca Mallamaci et al. · The Lancet · 2001 · 1.1K citations

Urology, Renal Function, Kidney Failure +9

A smoking–dependent risk of coronary artery disease associated with a polymorphism of the endothelial nitric oxide synthase gene

Xing L. Wang, Ah Siew Sim, Renee F. Badenhop et al. · Nature Medicine · 1996 · 565 citations

Tobacco Control, Vascular Disease, Cardiovascular Epidemiology +15

A Common Variant of the Endothelial Nitric Oxide Synthase (Glu<sup>298</sup>→Asp) Is a Major Risk Factor for Coronary Artery Disease in the UK

Aroon D. Hingorani, Chia Fan Liang, J Fatibene et al. · Circulation · 1999 · 529 citations