JNK1 is required for sulindac-mediated inhibition of cell proliferation and induction of apoptosis in vitro and in vivo

JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

Benoit Dérijard, Masahiko Hibi, I‐Huan Wu et al. · Cell · 1994 · 3.2K citations

Signal Transduction, Signaling Pathway, Cell Regulation +14

Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain.

Masahiko Hibi, Anning Lin, Tod Smeal et al. · Genes & Development · 1993 · 1.9K citations · Full text

Molecular Regulation, Molecular Biology, Serines 63 +18

Requirement of JNK for Stress- Induced Activation of the Cytochrome c-Mediated Death Pathway

Cathy Tournier, Patricia Hess, Derek Yang et al. · Science · 2000 · 1.7K citations

Selective interaction of JNK protein kinase isoforms with transcription factors.

Shreyasi Gupta, Tyler W. Barrett, Alan J. Whitmarsh et al. · The EMBO Journal · 1996 · 1.3K citations · Full text

Transcriptional Regulation, Signal Transduction, Signaling Pathway +12

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

Irma Sánchez, Rowland T. Hughes, Bruce J. Mayer et al. · Nature · 1994 · 978 citations

Reductive Stress, Systems Biology, Signal Transduction +12