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Overexpression of ALS-Associated p.M337V Human TDP-43 in Mice Worsens Disease Features Compared to Wild-type Human TDP-43 Mice

Jonathan Janssens, Hans Wils, Gernot Kleinberger, Geert Joris, Ivy Cuijt, Chantal Ceuterick‐de Groote, Christine Van Broeckhoven, Samir Kumar‐Singh

Molecular Neurobiology · 2013 · 109 citations · 43 references

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Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis

Manuela Neumann, Deepak M. Sampathu, Linda K. Kwong et al. · Science · 2006 · 6.5K citations

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

Tetsuaki Arai, Masato Hasegawa, Haruhiko Akiyama et al. · Biochemical and Biophysical Research Communications · 2006 · 2.7K citations

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TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis

Jemeen Sreedharan, Ian P. Blair, Vineeta B. Tripathi et al. · Science · 2008 · 2.6K citations · Full text

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ALS‐associated fused in sarcoma (FUS) mutations disrupt Transportin‐mediated nuclear import

Dorothee Dormann, Ramona Rodde, Dieter Edbauer et al. · The EMBO Journal · 2010 · 817 citations · Full text

TDP-43 Is Intrinsically Aggregation-prone, and Amyotrophic Lateral Sclerosis-linked Mutations Accelerate Aggregation and Increase Toxicity

Brian S. Johnson, David Snead, Jonathan J. Lee et al. · Journal of Biological Chemistry · 2009 · 787 citations · Full text

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