Detection of immunotoxicity using T-cell based cytokine reporter cell lines (“Cell Chip”)

Transcriptional Mechanisms Underlying Lymphocyte Tolerance

Fernando Macián, Francisco Garcı́a-Cózar, Sin‐Hyeog Im et al. · Cell · 2002 · 674 citations · Full text

Life Sciences, Cell Biology, Immunology +12

Thalidomide Costimulates Primary Human T Lymphocytes, Preferentially Inducing Proliferation, Cytokine Production, and Cytotoxic Responses in the CD8+ Subset

Patrick Haslett, Laura G. Corral, Matthew L. Albert et al. · The Journal of Experimental Medicine · 1998 · 573 citations · Full text

Life Sciences, Immunology, Pharmacology +17

A major house dust mite allergen disrupts the immunoglobulin E network by selectively cleaving CD23: innate protection by antiproteases.

C R Hewitt, Alan Brown, Barbara Hart et al. · The Journal of Experimental Medicine · 1995 · 274 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

The immunosuppressive drug thalidomide induces T helper cell type 2 (Th2) and concomitantly inhibits Th1 cytokine production in mitogen- and antigen-stimulated human peripheral blood mononuclear cell cultures

Sheena McHugh, Ian R. Rifkin, John Deighton et al. · Clinical & Experimental Immunology · 1995 · 265 citations

Medicine, Immunology, Pharmacology +16

Proteolytic Cleavage of CD25, the α Subunit of the Human T Cell Interleukin 2 Receptor, by Der p 1, a Major Mite Allergen with Cysteine Protease Activity

Oliver Schulz, Herb F. Sewell, Farouk Shakib · The Journal of Experimental Medicine · 1998 · 254 citations · Full text

Life Sciences, Immunology, Molecular Biology +17