E2F3 is the main target gene of the 6p22 amplicon with high specificity for human bladder cancer

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Functional Genomics, Engineering, Medicine +12

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The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F.

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Molecular Regulation, Molecular Biology, Prb Sequences +17

Stable suppression of gene expression by RNAi in mammalian cells

Patrick J. Paddison, Amy A. Caudy, Gregory J. Hannon · Proceedings of the National Academy of Sciences · 2002 · 549 citations · Full text

E2F3 activity is regulated during the cell cycle and is required for the induction of S phase

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