Irradiation-induced G2/M checkpoint response requires ERK1/2 activation

Mitotic and G ₂ Checkpoint Control: Regulation of 14-3-3 Protein Binding by Phosphorylation of Cdc25C on Serine-216

Cheng‐Yuan Peng, Paul R. Graves, Richard S. Thoma et al. · Science · 1997 · 1.3K citations

ATR-Mediated Checkpoint Pathways Regulate Phosphorylation and Activation of Human Chk1

Hui Zhao, Helen Piwnica‐Worms · Molecular and Cellular Biology · 2001 · 1.1K citations · Full text

The DNA Double-Strand Break Repair Gene hMRE11 Is Mutated in Individuals with an Ataxia-Telangiectasia-like Disorder

Grant S. Stewart, Richard S. Maser, Debra A. Bressan et al. · Cell · 1999 · 1.1K citations · Full text

Genome Instability, Mendelian Disorder, Genetic Disorder +11

Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine.

Jann N. Sarkaria, Ericka C. Busby, Randal S. Tibbetts et al. · PubMed · 1999 · 1K citations

Protein Kinase Activities, Atr Kinase Activities, Radiation Biology +17

Ataxia telangiectasia-mutated phosphorylates Chk2 <i>in vivo</i> and <i>in vitro</i>

Shuhei Matsuoka, Galit Rotman, Akira Ogawa et al. · Proceedings of the National Academy of Sciences · 2000 · 818 citations · Full text