NAD(P)H: Quinone Oxidoreductase 1 is Induced by Progesterone in Cardiomyocytes

A clinicopathologic analysis of adriamycin cardiotoxicity

Edward A. Lefrak, Jan Piťha, Sidney Rosenheim et al. · Cancer · 1973 · 1.5K citations

Cardiac Muscle, Cardiomyopathy, Heart Failure +13

Increase of NAD(P)H:quinone reductase by dietary antioxidants: possible role in protection against carcinogenesis and toxicity.

Ann M. Benson, Markus J. Hunkeler, Paul Talalay · Proceedings of the National Academy of Sciences · 1980 · 751 citations · Full text

Biochemistry, Medicine, Lipid Peroxidation +15

Redox cycling of anthracyclines by cardiac mitochondria. I. Anthracycline radical formation by NADH dehydrogenase.

Kelvin J.A. Davies, James H. Doroshow · Journal of Biological Chemistry · 1986 · 623 citations · Full text

Nadh Dehydrogenase, Molecular Biology, Mitochondrial Biology +18

Redox cycling of anthracyclines by cardiac mitochondria. II. Formation of superoxide anion, hydrogen peroxide, and hydroxyl radical.

James H. Doroshow, Kelvin J.A. Davies · Journal of Biological Chemistry · 1986 · 547 citations · Full text

Bioorganic Chemistry, Antimicrobial Chemotherapy, Chemical Biology +21

DT-diaphorase as a quinone reductase: A cellular control device against semiquinone and superoxide radical formation

Christina Lind, Paul Hochstein, Lars Ernster · Archives of Biochemistry and Biophysics · 1982 · 529 citations

Aldo-keto Reductase, Cellular Enzymology, Biochemistry +11