STAT3 is associated with lymph node metastasis in gastric cancer

Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention.

Ralf Buettner, Linda Mora, Richard Jove · PubMed · 2002 · 1K citations

Life Sciences, Cancer Biology, Oncology +9

IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation

Rachel M. McLoughlin, Brendan J. Jenkins, Dianne Grail et al. · Proceedings of the National Academy of Sciences · 2005 · 333 citations · Full text

Life Sciences, Immunology, Pathology +17

STAT3 is constitutively activated and supports cell survival in association with survivin expression in gastric cancer cells

Naoki Kanda, Hiroshi Seno, Yoshitaka Konda et al. · Oncogene · 2004 · 306 citations · Full text

Medicine, Molecular Biology, Oncology +13

Signal Transducer and Activator of Transcription 3 Is Required for the Oncogenic Effects of Non–Small-Cell Lung Cancer–Associated Mutations of the Epidermal Growth Factor Receptor

James V. Alvarez, Heidi Greulich, William R. Sellers et al. · Cancer Research · 2006 · 240 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Identification of a Genetic Signature of Activated Signal Transducer and Activator of Transcription 3 in Human Tumors

James V. Alvarez, Phillip G. Febbo, Sridhar Ramaswamy et al. · Cancer Research · 2005 · 208 citations · Full text

Medicine, Molecular Biology, Oncology +16