Differential involvement of μ-opioid receptor subtypes in endomorphin-1- and -2-induced antinociception

A SIMPLIFIED METHOD OF EVALUATING DOSE-EFFECT EXPERIMENTS

J.T. LITCHFIELD, Frank Wilcoxon · Journal of Pharmacology and Experimental Therapeutics · 1949 · 7.3K citations

Public Health, Biostatistics, Pharmacology +12

Intrathecal morphine in mice: A new technique

Janice L.K. Hylden, George L. Wilcox · European Journal of Pharmacology · 1980 · 1.9K citations

Medicine, Pharmacokinetics, Pharmacology +12

Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the µ-opioid-receptor gene

Hans W. D. Matthes, Rafaël Maldonado, Frédéric Simonin et al. · Nature · 1996 · 1.7K citations

Medicine, Neuroscience, Pharmacology +17

PHARMACOLOGICAL EFFECTS PRODUCED BY INTRACEREBRAL INJECTION OF DRUGS IN THE CONSCIOUS MOUSE

Thomas J. Haley, WF McCormick · British Journal of Pharmacology and Chemotherapy · 1957 · 1.5K citations · Full text

Medicine, Neuroscience, Pharmacology +12

A potent and selective endogenous agonist for the µ-opiate receptor

James E. Zadina, Laszlo Hackler, Lin-Jun Ge et al. · Nature · 1997 · 1.3K citations

Medicine, Medicinal Chemistry, Pharmacology +12