Genetics of fat tissue accumulation in pigs: a comparative approach

Congenital leptin deficiency is associated with severe early-onset obesity in humans

Carl Montague, I. Sadaf Farooqi, Jonathan P. Whitehead et al. · Nature · 1997 · 2.9K citations · Full text

Medicine, Endocrinology, Pediatrics +11

A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

Karine Clément, Christian Vaisse, Najiba Lahlou et al. · Nature · 1998 · 2.4K citations

Medicine, Endocrinology, Genetics +13

Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans

Heiko Krude, Heike Biebermann, W. A. P. Luck et al. · Nature Genetics · 1998 · 1.7K citations

Life Sciences, Endocrinology, Genetics +17

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

Elizabeth K. Speliotes · Nature Genetics · 2008 · 1.7K citations · Full text

Medicine, Neurobiology, Neuroscience +12

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity

G. Bragi Walters, Daníel F. Guðbjartsson, Valgerður Steinthórsdóttir et al. · Nature Genetics · 2008 · 1.4K citations

Life Sciences, Genetics, Molecular Genetics +10