Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

Panos Deloukas, Audrey Duncanson, Dominic Kwiatkowski et al. · Nature · 2007 · 9.6K citations · Full text

Life Sciences, Genetics, Molecular Genetics +12

A Common Variant in the <i>FTO</i> Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity

Timothy M. Frayling, Nicholas J. Timpson, Michael N. Weedon et al. · Science · 2007 · 4.5K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Merlin—rapid analysis of dense genetic maps using sparse gene flow trees

Gonçalo R. Abecasis, Stacey S. Cherny, William Cookson et al. · Nature Genetics · 2001 · 3.4K citations

Life Sciences, Bioinformatics, Genetics +15

Targeted Disruption of the Melanocortin-4 Receptor Results in Obesity in Mice

Dennis Huszar, Catherine Lynch, Victoria Fairchild-Huntress et al. · Cell · 1997 · 3K citations · Full text

Medicine, Endocrinology, Neuroscience +11

A new multipoint method for genome-wide association studies by imputation of genotypes

Jonathan Marchini, Bryan Howie, Simon Myers et al. · Nature Genetics · 2007 · 2.7K citations

Life Sciences, Biostatistics, Genetics +12