Concepedia

Protein tyrosine phosphatases in signal transduction

Benjamin G. Neel, N. K. Tonks

Current Opinion in Cell Biology · 1997 · 763 citations · 71 references

DOI

Concepts

References

71

MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo

Hong Sun, Catherine H. Charles, Lester F. Lau et al. · Cell · 1993 · 1.2K citations

, , +13

A two-component system that regulates an osmosensing MAP kinase cascade in yeast

Tatsuya Maeda, Susannah M. Wurgler‐Murphy, Haruo Saito · Nature · 1994 · 1.1K citations

, , +14

Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals

Ursula Klingmüller, Ulrike Lorenz, Lewis C. Cantley et al. · Cell · 1995 · 939 citations · Full text

, , +14

Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor FeγRIIB

Masao Ono, Silvia Bolland, Paul Tempst et al. · Nature · 1996 · 785 citations

, , +16

Development of “substrate-trapping” mutants to identify physiological substrates of protein tyrosine phosphatases

Andrew Flint, Tony Tiganis, David Barford et al. · Proceedings of the National Academy of Sciences · 1997 · 779 citations · Full text

, , +17