Angewandte Chemie International Edition · 2003 · 55 citations · 24 references
Combinatorial ChemistryBioorganic ChemistryEngineeringGlycobiologyOrganic ChemistryPolysaccharideBiosynthesisMeyers–chan ProcedureStereoselective SynthesisC-linked DisaccharidesGlycosylationTandem Halogenation/ramberg–bäcklund ReactionBiochemistryDiversity-oriented SynthesisBioconjugationNatural Product SynthesisBiomolecular EngineeringSimplified Ramberg–bäcklund ApproachNatural SciencesCarbohydrate-protein Interaction
Eight illustrious organic chemists in one pot! A route from protected monosaccharides to novel C-glycosides and C-linked disaccharides is described which involves tandem Horner–Wadsworth–Emmons/conjugate addition (Michael-type), followed by tandem halogenation/Ramberg–Bäcklund reaction using the Meyers–Chan procedure (see scheme, R=protected saccharide).
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Hiroshi Ohrui, Gordon H. Jones, J. G. Moffatt et al. · Journal of the American Chemical Society · 1975 · 255 citations