Concepedia

AAV-mediated gene targeting methods for human cells

Iram Khan, Roli K. Hirata, David W. Russell

Nature Protocols · 2011 · 189 citations · 62 references

DOI

Concepts

References

62

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

Kirk R. Thomas, Mario R. Capecchi · Cell · 1987 · 2.4K citations

, , +12

Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield

Sergei Zolotukhin, Barry J. Byrne, Emily Grace Mason et al. · Gene Therapy · 1999 · 1.3K citations

, , +13

Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system.

Robert B. DuBridge, Po-Cheng Tang, H C Hsia et al. · Molecular and Cellular Biology · 1987 · 1.1K citations · Full text

, , +16

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

Dirk Hockemeyer, Frank Soldner, Caroline Beard et al. · Nature Biotechnology · 2009 · 1.1K citations · Full text

, , +14

Insertion of DNA sequences into the human chromosomal β-globin locus by homologous recombination

Oliver Smithies, Ronald G. Gregg, Sallie S. Boggs et al. · Nature · 1985 · 995 citations

, , +7