A sensitive and relevant model for evaluating anti-inflammatory activity—papaya latex-induced rat paw inflammation

Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like Drugs

John R. Vane · Nature New Biology · 1971 · 8.6K citations

Aspirin-like Drugs, Prostaglandin Synthesis, Biochemistry +8

Studies of the mediators of the acute inflammatory response induced in rats in different sites by carrageenan and turpentine

Michelino Di Rosa, J. P. Giroud, D. A. Willoughby · The Journal of Pathology · 1971 · 1.4K citations

Inflammation, Different Sites, Anti-inflammatory +6

Anti-inflammatory steroids induce biosynthesis of a phospholipase A2 inhibitor which prevents prostaglandin generation

R.J. Flower, Geoffrey J. Blackwell · Nature · 1979 · 926 citations

Inflammation, Anti-inflammatory, Prostaglandin Generation +13

Macrocortin: a polypeptide causing the anti-phospholipase effect of glucocorticoids

Geoffrey J. Blackwell, Rosa Carnuccio, Massimo Di Rosa et al. · Nature · 1980 · 921 citations

Inflammation, Anti-inflammatory, Medicine +7

THE PARTICULATE HYDROLASES OF MACROPHAGES

Zanvil A. Cohn, Edith Wiener · The Journal of Experimental Medicine · 1963 · 269 citations · Full text

Macrophage Granules, Cell Autophagy, Macrophage Hydrolase-containing Granules +15