Macrocortin: a polypeptide causing the anti-phospholipase effect of glucocorticoids

Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like Drugs

John R. Vane · Nature New Biology · 1971 · 8.6K citations

Life Sciences, Medicinal Chemistry, Pharmacology +10

Aspirin Selectively Inhibits Prostaglandin Production in Human Platelets

J. Bryan Smith, A.L. Willis · Nature New Biology · 1971 · 1.5K citations

Medicine, Pharmacology, Pharmacotherapy +14

Indomethacin and Aspirin abolish Prostaglandin Release from the Spleen

S. H. Ferreira, Salvador Moncada, John R. Vane · Nature New Biology · 1971 · 934 citations

Veterinary Medicine, Pharmacology, Inflammation +5

Anti-inflammatory steroids induce biosynthesis of a phospholipase A2 inhibitor which prevents prostaglandin generation

R.J. Flower, Geoffrey J. Blackwell · Nature · 1979 · 929 citations

Life Sciences, Biochemistry, Pharmacology +16

Inhibition of arachidonic acid release from cells as the biochemical action of anti-inflammatory corticosteroids.

S L Hong, Lawrence Levine · Proceedings of the National Academy of Sciences · 1976 · 571 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17