Highly flexible and efficient synthesis of the GABAB enhancer 4-(2-hexylsulfanyl-6-methyl-pyrimidin-4-ylmethyl)-morpholine

New method for the methylation of amines

Richard F. Borch, Aviv Hassid · The Journal of Organic Chemistry · 1972 · 323 citations

Engineering, Altmetric Attention Score, Bibliometrics +17

A new general method for preparation of N-methoxy-N-methylamides. Application in direct conversion of an ester to a ketone

J. Michael Williams, Ronald B. Jobson, Nobuyoshi Yasuda et al. · Tetrahedron Letters · 1995 · 192 citations

Direct Conversion, New General Method, Engineering +8

An improved method for reductive alkylation of amines using titanium(IV) isopropoxide and sodium cyanoborohydride

Ronald J. Mattson, Kahnie M. Pham, David J. Leuck et al. · The Journal of Organic Chemistry · 1990 · 185 citations

Improved Method, Sodium Cyanoborohydride, Engineering +18

Novel Solution- and Solid-Phase Strategies for the Parallel and Combinatorial Synthesis of Small-Molecular-Weight Compound Libraries

Alexander Chucholowski, Thierry Masquelin, Daniel Obrecht et al. · CHIMIA International Journal for Chemistry · 1996 · 71 citations · Full text

Combinatorial Chemistry, Bioorganic Chemistry, Small-molecular-weight Compound Libraries +19

Reductive Amination of Piperidines with Aldehydes Using Borane-Pyridine

Alan E. Moormann · Synthetic Communications · 1993 · 68 citations

Inorganic Chemistry, Chemical Engineering, Engineering +9