Concepedia

CpG motifs as immune adjuvants

Dennis M. Klinman, Kerry M. Barnhart, Jacqueline Conover

Vaccine · 1999 · 310 citations · 19 references

DOI

Concepts

References

19

CpG motifs in bacterial DNA trigger direct B-cell activation

Arthur Μ. Krieg, Ae‐Kyung Yi, Sara Matson et al. · Nature · 1995 · 3.5K citations

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Interferon-γ and B Cell Stimulatory Factor-1 Reciprocally Regulate Ig Isotype Production

Clifford M. Snapper, William E. Paul · Science · 1987 · 1.9K citations

, , +17

CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma.

Dennis M. Klinman, Ae‐Kyung Yi, Serge L. Beaucage et al. · Proceedings of the National Academy of Sciences · 1996 · 1.5K citations

, , +17

Immunostimulatory DNA Sequences Necessary for Effective Intradermal Gene Immunization

Yukio Sato, Mark Roman, Helen Tighe et al. · Science · 1996 · 1.1K citations

, , +17

Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes

Giorgio Trinchieri · Blood · 1994 · 1.1K citations · Full text

, , +17