Concepedia

Antigen-adjuvant Interactions

Antigen-Adjuvant Interactions is a mechanistic process in vaccine formulation whereby an adjuvant enhances the immunogenicity of an antigen through physical, chemical, or biological engagement that modulates antigen presentation, immune recognition, or inflammatory signaling, thereby distinguishing it from isolated antigen or adjuvant effects.

383

Publications

18.7K

Citations

1.9K

Authors

578

Institutions

Publications per year

2017–2026

72

Parents

Publications

383

Mechanisms of Action of Adjuvants

Sunita Awate, Lorne A. Babiuk, George Mutwiri · Frontiers in Immunology · 2013 · 730 citations · Full text

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MF59 Adjuvant Enhances Diversity and Affinity of Antibody-Mediated Immune Response to Pandemic Influenza Vaccines

Surender Khurana, Nitin Verma, Jonathan W. Yewdell et al. · Science Translational Medicine · 2011 · 356 citations

, , +17

CpG motifs as immune adjuvants

Dennis M. Klinman, Kerry M. Barnhart, Jacqueline Conover · Vaccine · 1999 · 310 citations

, , +14

Montanide ISA 720 and 51: a new generation of water in oil emulsions as adjuvants for human vaccines

J. Aucouturier, Laurent Dupuis, S. Deville et al. · Expert Review of Vaccines · 2002 · 305 citations

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The mode of action of immunologic adjuvants.

Jean‐Noël Freund · PubMed · 1956 · 295 citations

, , +12

1–5 of 383

Authors

1.9K

  1. SL
    Stanley L. Hem

    Purdue University West Lafayette, United States

    14 publications · 1.3K citations

    13

    h-index

  2. HH
    Harm HogenEsch

    Purdue University West Lafayette, United States

    10 publications · 1.1K citations

    10

    h-index

  3. DT
    Derek T. O’Hagan

    Novartis (United States), United States

    6 publications · 500 citations

    6

    h-index

  4. HG
    Hana Golding

    Center for Biologics Evaluation and Research, United States

    4 publications · 764 citations

    4

    h-index

  5. LA
    Lorne A. Babiuk

    University of Saskatchewan, Canada

    4 publications · 817 citations

    4

    h-index

1–5 of 1.9K

Institutions

578

  1. Purdue University West Lafayette

    West Lafayette, United States

    15 h-index

    50 publications

    5K citations

  2. National Institutes of Health

    Bethesda, United States

    8 h-index

    26 publications

    1.9K citations

  3. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    7 h-index

    16 publications

    1.5K citations

  4. Infectious Disease Research Institute

    Seattle, United States

    7 h-index

    27 publications

    1.4K citations

  5. The University of Melbourne

    Melbourne, Australia

    6 h-index

    14 publications

    363 citations

  6. Novartis (Italy)

    Milan, Italy

    6 h-index

    18 publications

    1.9K citations

  7. Novartis (Switzerland)

    Basel, Switzerland

    6 h-index

    12 publications

    2.5K citations

  8. Sanofi (France)

    Paris, France

    5 h-index

    14 publications

    275 citations

1–8 of 578

Venues

  1. Vaccine

    74 publications · 4.8K citations

    43

    h-index

  2. PubMed

    Repository · 31 publications · 1.2K citations

    18

    h-index

  3. The Journal of Immunology

    JI · 15 publications · 782 citations

    13

    h-index

  4. Infection and Immunity

    IAI · 8 publications · 177 citations

    8

    h-index

  5. Human Vaccines & Immunotherapeutics

    HV&I · 8 publications · 179 citations

    8

    h-index

1–5