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Small molecule inhibitors of the CCR2b receptor. Part 1: Discovery and optimization of homopiperazine derivatives

Minoru Imai, Tatsuki Shiota, Ken-ichiro Kataoka, Christine M. Tarby, Wilna J. Moree, Takaharu Tsutsumi, Masaki Sudo, Michele M. Ramirez‐Weinhouse, Daniel D. Comer, Chung‐Ming Sun,

Bioorganic & Medicinal Chemistry Letters · 2004 · 27 citations · 19 references

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19

Decreased lesion formation in CCR2−/− mice reveals a role for chemokines in the initiation of atherosclerosis

Landin Boring, Jennifa Gosling, Michael D. Cleary et al. · Nature · 1998 · 2K citations

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Monocyte chemoattractant protein 1 acts as a T-lymphocyte chemoattractant.

Michelle Woldemar Carr, Stephen J. Roth, Ed Luther et al. · Proceedings of the National Academy of Sciences · 1994 · 1.2K citations

, , +14

Purification and characterization of a novel monocyte chemotactic and activating factor produced by a human myelomonocytic cell line.

Kouji Matsushima, C G Larsen, G C Dubois et al. · The Journal of Experimental Medicine · 1989 · 768 citations · Full text

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Human monocyte chemoattractant protein‐1 (MCP‐1) Full‐length cDNA cloning, expression in mitogen‐stimulated blood mononuclear leukocytes, and sequence similarity to mouse competence gene JE

Teizo Yoshimura, Naoya Yuhki, S. Moore et al. · FEBS Letters · 1989 · 596 citations

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RANTES and Monocyte Chemoattractant Protein–1 (MCP-1) Play an Important Role in the Inflammatory Phase of Crescentic Nephritis, but Only MCP-1 Is Involved in Crescent Formation and Interstitial Fibrosis

Clare M. Lloyd, Andrew W. Minto, Martin E. Dorf et al. · The Journal of Experimental Medicine · 1997 · 496 citations · Full text

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