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Potent, orally active inhibitors of lipoprotein-associated phospholipase A2: 1-(biphenylmethylamidoalkyl)-pyrimidones

Helen Boyd, Stephen C. M. Fell, Deirdre M. B. Hickey, Robert J. Ife, Colin A. Leach, Colin H. Macphee, Kevin J. Milliner, Ivan L. Pinto, D. Anthony Rawlings, Stephen A. Smith,

Bioorganic & Medicinal Chemistry Letters · 2002 · 29 citations · 4 references

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4

Lipoprotein-Associated Phospholipase A<sub>2</sub>as an Independent Predictor of Coronary Heart Disease

Chris J. Packard, D S O’Reilly, Muriel Caslake et al. · New England Journal of Medicine · 2000 · 813 citations · Full text

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Purification, Properties, Sequencing, and Cloning of a Lipoprotein-Associated, Serine-Dependent Phospholipase Involved in the Oxidative Modification of Low-Density Lipoproteins

David G. Tew, Christopher Southan, Simon Q.J. Rice et al. · Arteriosclerosis Thrombosis and Vascular Biology · 1996 · 163 citations

, , +11

N-1 substituted pyrimidin-4-ones: novel, orally active inhibitors of lipoprotein-associated phospholipase A2

Helen Boyd, Stephen C. M. Fell, Sean T. Flynn et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 28 citations · Full text

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1-(Arylpiperazinylamidoalkyl)-pyrimidones: orally active inhibitors of lipoprotein-associated phospholipase A 2

Jackie C. Bloomer, Helen Boyd, Deirdre M.B. Hickey et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 20 citations · Full text

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