Colin A. Leach

Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase, generates two bioactive products during the oxidation of low-density lipoprotein: use of a novel inhibitor

Colin H. Macphee, Kitty Moores, Helen Boyd et al. · Biochemical Journal · 1999 · 337 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

The identification of clinical candidate SB-480848: a potent inhibitor of lipoprotein-associated phospholipase A2

Josie A. Blackie, Jackie C. Bloomer, Murray J. B. Brown et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 130 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +6

Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase, generates two bioactive products during the oxidation of low-density lipoprotein: use of a novel inhibitor

Colin H. Macphee, Kitty Moores, Helen Boyd et al. · Biochemical Journal · 1999 · 102 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Reversible inhibitors of the gastric (H+/K+)-ATPase. 1. 1-Aryl-4-methylpyrrolo[3,2-c]quinolines as conformationally restrained analogs of 4-(arylamino)quinolines

Thomas H. Brown, Robert J. Ife, David J. Keeling et al. · Journal of Medicinal Chemistry · 1990 · 58 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +16

Reversible inhibitors of the gastric (H+/K+)-ATPase. 2. 1-Arylpyrrolo[3,2-c]quinolines: effect of the 4-substituent

Colin A. Leach, Thomas H. Brown, Robert J. Ife et al. · Journal of Medicinal Chemistry · 1992 · 56 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17