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1-(Arylpiperazinylamidoalkyl)-pyrimidones: orally active inhibitors of lipoprotein-associated phospholipase A 2

Jackie C. Bloomer, Helen Boyd, Deirdre M.B. Hickey, Robert J. Ife, Colin A. Leach, Colin H. Macphee, Kevin J. Milliner, Ivan L. Pinto, D. Anthony Rawlings, Stephen A. Smith,

Bioorganic & Medicinal Chemistry Letters · 2001 · 20 citations · 4 references

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4

Lipoprotein-Associated Phospholipase A<sub>2</sub>as an Independent Predictor of Coronary Heart Disease

Chris J. Packard, D S O’Reilly, Muriel Caslake et al. · New England Journal of Medicine · 2000 · 813 citations · Full text

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Purification, Properties, Sequencing, and Cloning of a Lipoprotein-Associated, Serine-Dependent Phospholipase Involved in the Oxidative Modification of Low-Density Lipoproteins

David G. Tew, Christopher Southan, Simon Q.J. Rice et al. · Arteriosclerosis Thrombosis and Vascular Biology · 1996 · 163 citations

, , +11

N-1 substituted pyrimidin-4-ones: novel, orally active inhibitors of lipoprotein-associated phospholipase A2

Helen Boyd, Stephen C. M. Fell, Sean T. Flynn et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 28 citations · Full text

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The identification of a potent, water soluble inhibitor of lipoprotein-associated phospholipase A2

Helen Boyd, Beverley Hammond, Deirdre M.B. Hickey et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 11 citations · Full text

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