Anti-inflammatory effects of genistein via suppression of the toll-like receptor 4-mediated signaling pathway in lipopolysaccharide-stimulated BV2 microglia

Genistein, a specific inhibitor of tyrosine-specific protein kinases.

Tetsu Akiyama, Junko Ishida, Shizue Nakagawa et al. · Journal of Biological Chemistry · 1987 · 3.7K citations · Full text

Activation of microglial cells by β-amyloid protein and interferon-γ

Lucia Meda, Marco A. Cassatella, Györgyi I. Szendrei et al. · Nature · 1995 · 1.3K citations

Inflammation, Medicine, Brain-immune Interaction +6

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

Katherine A. Fitzgerald, Eva M. Pålsson‐McDermott, Andrew Bowie et al. · Nature · 2001 · 1.3K citations

Toll-like Receptors, Immunogenetics, Molecular Immunology +5

Lipopolysaccharide Stimulates the MyD88-Independent Pathway and Results in Activation of IFN-Regulatory Factor 3 and the Expression of a Subset of Lipopolysaccharide-Inducible Genes

Taro Kawai, Osamu Takeuchi, Takashi Fujita et al. · The Journal of Immunology · 2001 · 1.1K citations · Full text

Microglial Activation and Chronic Neurodegeneration

Melinda E. Lull, Michelle L. Block · Neurotherapeutics · 2010 · 1K citations · Full text