Concepedia

Hepatic miR-378 targets p110α and controls glucose and lipid homeostasis by modulating hepatic insulin signalling

Wei Liu, Hongchao Cao, Ye Cheng, Cunjie Chang, Minghua Lü, Yanyan Jing, Duo Zhang, Xuan Yao, Zhengjun Duan, Yucheng Wang,

Nature Communications · 2014 · 115 citations · 27 references

DOIFull text

Open access

Concepts

References

27

Insulin signalling and the regulation of glucose and lipid metabolism

Alan R. Saltiel, C. Ronald Kahn · Nature · 2001 · 5.3K citations · Full text

, , +14

Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)

Han Cho, James Mu, Jason K. Kim et al. · Science · 2001 · 1.8K citations

, , +17

Loss of Insulin Signaling in Hepatocytes Leads to Severe Insulin Resistance and Progressive Hepatic Dysfunction

M.Dodson Michael, Rohit Kulkarni, Catherine Postic et al. · Molecular Cell · 2000 · 1.2K citations · Full text

, , +17

MicroRNAs 103 and 107 regulate insulin sensitivity

Mirko Trajkovski, Jean Hausser, Jürgen Soutschek et al. · Nature · 2011 · 988 citations · Full text

, , +14

Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes

Marc Foretz, C Guichard, Pascal Ferré et al. · Proceedings of the National Academy of Sciences · 1999 · 735 citations

, , +16