Asymmetric synthesis and absolute stereochemistry of LY248686

A new reagent for the selective, high-yield N-dealkylation of tertiary amines: improved syntheses of naltrexone and nalbuphine

R. A. Olofson, Jonathan T. Martz, J.‐P. G. Senet et al. · The Journal of Organic Chemistry · 1984 · 345 citations

Medicinal Chemistry, Molecular Sciences, Engineering +15

Enantioselective and practical syntheses of R- and S-fluoxetines

E. J. Corey, Gregory A. Reichard · Tetrahedron Letters · 1989 · 187 citations

Medicinal Chemistry, Practical Syntheses, Natural Sciences +5

Asymmetric reductions with chiral reagents from lithium aluminum hydride and (+)-(2S,3R)-4-dimethylamino-3-methyl-1,2-diphenyl-2-butanol

Shozo Yamaguchi, Harry S. Mosher · The Journal of Organic Chemistry · 1973 · 172 citations

Chemical Engineering, Engineering, Altmetric Attention Score +12

The absolute configurations and pharmacological activities of the optical isomers of fluoxetine, a selective serotonin-uptake inhibitor

David W. Robertson, Joseph H. Krushinski, R W Fuller et al. · Journal of Medicinal Chemistry · 1988 · 160 citations

Psychotropic Medication, Psychopharmacology, Selective Serotonin-uptake Inhibitor +20

Asymmetric synthesis of both enantiomers of tomoxetine and fluoxetine. Selective reduction of 2,3-epoxycinnamyl alcohol with Red-Al

Yun Gao, K. Barry Sharpless · The Journal of Organic Chemistry · 1988 · 144 citations

Pharmaceutical Science, 2,3-Epoxycinnamyl Alcohol, Altmetric Attention Score +18