Concepedia

An oncolytic adenovirus enhances antiangiogenic and antitumoral effects of a replication-deficient adenovirus encoding endostatin by rescuing its selective replication in nasopharyngeal carcinoma cells

Ran-Yi Liu, Ling Zhou, Yanling Zhang, Bi-Jun Huang, Miao-La Ke, Jiemin Chen, Li-xia Li, Xiang Fu, Jiang-Xue Wu, Wenlin Huang

Biochemical and Biophysical Research Communications · 2013 · 11 citations · 12 references

DOI

Concepts

References

12

ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents

Carla Heise, Adam Sampson-Johannes, Angelica Williams et al. · Nature Medicine · 1997 · 944 citations

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China Approves World's First Oncolytic Virus Therapy For Cancer Treatment

Ken Garber · JNCI Journal of the National Cancer Institute · 2006 · 472 citations · Full text

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Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumor selectivity

Clodagh C. O’Shea, Leisa Johnson, Bridget Bagus et al. · Cancer Cell · 2004 · 378 citations · Full text

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Nasopharyngeal carcinoma in Indonesia: epidemiology, incidence,signs, and symptoms at presentation

Marlinda Adham, Antonius Kurniawan, Arina Ika Muhtadi et al. · Chinese Journal of Cancer · 2012 · 350 citations · Full text

Antiangiogenic gene therapy of cancer utilizing a recombinant adenovirus to elevate systemic endostatin levels in mice.

Andrew L. Feldman, Nicholas P. Restifo, H. Richard Alexander et al. · PubMed · 2000 · 120 citations

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