Macrophage insulin receptor deficiency increases ER stress-induced apoptosis and necrotic core formation in advanced atherosclerotic lesions

Biochemistry and molecular cell biology of diabetic complications

Michael Brownlee · Nature · 2001 · 8.9K citations

Diabetes Management, Diabetes, Pathology +6

Endoplasmic Reticulum Stress Links Obesity, Insulin Action, and Type 2 Diabetes

Umut Özcan, Qiong Cao, Erkan Yılmaz et al. · Science · 2004 · 3.8K citations

Metabolic Disorder, Er Stress, Insulin Receptor +18

Reactive Oxygen Species Promote TNFα-Induced Death and Sustained JNK Activation by Inhibiting MAP Kinase Phosphatases

Hideaki Kamata, Shinichi Honda, Shin Maeda et al. · Cell · 2005 · 1.8K citations · Full text

Inflammation, Redox Signaling, Signal Transduction +12

TRB3, a novel ER stress‐inducible gene, is induced via ATF4–CHOP pathway and is involved in cell death

Nobumichi Ohoka, Satoshi Yoshii, Takayuki Hattori et al. · The EMBO Journal · 2005 · 992 citations · Full text

The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages

Bo Feng, Pin Mei Yao, Yankun Li et al. · Nature Cell Biology · 2003 · 865 citations

Inflammation, Oxysterol, Cell Signaling +14