Neurology · 2002 · 41 citations · 8 references
PharmacyNeurologyToxicologyHemodialysisNeuropathologyPoisoning DiagnosisCentral Nervous System ToxicityDemyelinating DiseasesDemyelinating DisordersMyelin ToxicityNecrosisPeripheral Nervous System ToxicityAcute Central Nervous System ToxicityCentral Nervous System Myelin ToxicityFatal PoisoningGross Pathologic ExaminationMotor Impairment In IntoxicationOverdose ToxicityPeripheral Myelin ToxicityRenal Failure Management
The authors report a 57-year-old man who survived 18 days after swallowing an 8-oz. can of Sterno in a suicide attempt. Two days after ingestion, he developed confusion and acute renal failure requiring hemodialysis, followed on day 8 by a delayed but rapidly evolving ascending paralysis. Pathologic examination showed severe demyelination, with lesser axonal damage, of virtually all cranial and peripheral nerves sampled and sparing of central myelin. The diethylene glycol in the Sterno was considered responsible for this intoxication.
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Fatal renal failure caused by diethylene glycol in paracetamol elixir: the Bangladesh epidemic
Mohammed Hanif, Mahmoud Mobarak, Anne Ronan et al. · BMJ · 1995 · 168 citations
Medicine, Pediatrics, Toxicology +15