Subfatin is a Novel Adipokine and Unlike Meteorin in Adipose and Brain Expression

Positional cloning of the mouse obese gene and its human homologue

Yiying Zhang, Ricardo Proenca, Margherita Maffei et al. · Nature · 1994 · 13.3K citations

Obesity, Metabolic Syndrome, Knockout Mouse +10

Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance

Gökhan S. Hotamışlıgil, Narinder S. Shargill, Bruce M. Spiegelman · Science · 1993 · 7.4K citations

The hormone resistin links obesity to diabetes

Claire M. Steppan, Shannon T. Bailey, Savitha Bhat et al. · Nature · 2001 · 4.7K citations

Insulin Resistance, Metabolic Syndrome, Obesity +10

Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys

Ricki J. Colman, Rozalyn M. Anderson, Sterling C. Johnson et al. · Science · 2009 · 2.2K citations · Full text

Nutrition, Anti-aging, Aging +17

Induction of autophagy contributes to the neuroprotection of nicotinamide phosphoribosyltransferase in cerebral ischemia

Pei Wang, Yun‐Feng Guan, Hui Du et al. · Autophagy · 2012 · 318 citations · Full text

Cell Death, Oxidative Stress, Neuroinflammation +21