Sirolimus and Tacrolimus Trough Concentrations and Dose Requirements after Kidney Transplantation in Relation to CYP3A5 and MDR1 Polymorphisms and Steroids - Concepedia

Concepedia

Publication | Closed Access

Sirolimus and Tacrolimus Trough Concentrations and Dose Requirements after Kidney Transplantation in Relation to CYP3A5 and MDR1 Polymorphisms and Steroids

114

Citations

31

References

2005

Year

Michel Mourad, Georges Mourad, Pierre Wallemacq, Val rie Garrigue, Christophe Van Bellingen, Val rie Van Kerckhove, Martine De Meyer, Jacques Malaise, Djamila Chaïb Eddour, Dominique Lison,

Transplantation

Abstract

Unlike tacrolimus, sirolimus adjusted trough concentrations and dose requirements seem not affected by CYP3A5 and MDR1 polymorphisms. Adjusted-prednisone dose has a significant impact on tacrolimus and sirolimus dose requirements.

References

	Year	Citations

Page 1