Concepedia

Respiratory virus induction of alpha‐, beta‐ and lambda‐interferons in bronchial epithelial cells and peripheral blood mononuclear cells

Musa Khaitov, Vasile Laza‐Stanca, Michael R. Edwards, Ross P. Walton, Gernot Rohde, Marco Contoli, Alberto Papi, L Stanciu, Sergei V. Kotenko, Sebastian L. Johnston

Allergy · 2009 · 211 citations · 32 references

DOIFull text

Open access

Abstract

We conclude that interferon-lambdas are likely the principal interferons produced during innate responses to respiratory viruses in BECs and interferon-alphas in PBMCs, while interferon-beta is produced by both cell types.

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