The Drosophila immune response against Gram-negative bacteria is mediated by a peptidoglycan recognition protein

The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults

Bruno Lemaître, Émmanuelle Nicolas, Lydia Michaut et al. · Cell · 1996 · 3.9K citations · Full text

Biology, Potent Antifungal Response, Natural Sciences +10

<i>Drosophila</i> host defense: Differential induction of antimicrobial peptide genes after infection by various classes of microorganisms

Bruno Lemaître, Jean‐Marc Reichhart · Proceedings of the National Academy of Sciences · 1997 · 1K citations · Full text

Antifungal Peptides, Innate Immune System, Immunology +17

Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein

Tatiana Michel, Jean‐Marc Reichhart, Jules A. Hoffmann et al. · Nature · 2001 · 778 citations

Virulence Factor, Pathogenesis, Immunology +7

A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense.

Bruno Lemaître, Elisabeth KROMER‐METZGER, Lydia Michaut et al. · Proceedings of the National Academy of Sciences · 1995 · 623 citations · Full text

Microbial Pathogens, Genetics, Innate Immune System +19

A family of peptidoglycan recognition proteins in the fruit fly<i>Drosophila melanogaster</i>

Thomas Werner, Gang Liu, Daiwu Kang et al. · Proceedings of the National Academy of Sciences · 2000 · 544 citations