Cleavage of Bax Enhances Its Cell Death Function

Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked

Jie Yang, Xuesong Liu, Kapil N. Bhalla et al. · Science · 1997 · 4.9K citations

Mitophagy, Apoptosis, Cell Death +17

Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis

Honglin Li, Hong Zhu, Chi-jie Xu et al. · Cell · 1998 · 4.4K citations · Full text

Mitophagy, Signal Transduction, Mitochondrial Damage +12

Bid, a Bcl2 Interacting Protein, Mediates Cytochrome c Release from Mitochondria in Response to Activation of Cell Surface Death Receptors

Xu Luo, I. Imawati Budihardjo, Hua Zou et al. · Cell · 1998 · 3.6K citations · Full text

Mitophagy, Signal Transduction, Biochemistry +10

Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

Shigeomi Shimizu, Masashi Narita, Yoshihide Tsujimoto et al. · Nature · 1999 · 2.2K citations

Molecular Physiology, Signal Transduction, Mitochondrial Function +14

Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization

Ella Bossy‐Wetzel · The EMBO Journal · 1998 · 1.2K citations · Full text

Signal Transduction, Mitochondrial Function, Biochemistry +11