Concepedia

Bax Oligomerization

Bax Oligomerization is a molecular process in which the pro-apoptotic protein Bax undergoes conformational activation and self-assembly into higher-order oligomeric complexes within the mitochondrial outer membrane, thereby facilitating membrane permeabilization and the release of cytochrome c during intrinsic apoptosis.

387

Publications

38.9K

Citations

1.9K

Authors

564

Institutions

Publications per year

2017–2026

49

Parents

Publications

387

Bid Induces the Oligomerization and Insertion of Bax into the Outer Mitochondrial Membrane

Robert Eskes, Solange Desagher, Bruno Antonsson et al. · Molecular and Cellular Biology · 2000 · 1.2K citations

, , +9

Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

Atan Gross, Jennifer Jockel, Michael C. Wei et al. · The EMBO Journal · 1998 · 1.1K citations · Full text

, , +15

Multiple Bcl-2 family members demonstrate selective dimerizations with Bax.

Thomas W. Sedlak, Zoltán N. Oltvai, Elizabeth Yang et al. · Proceedings of the National Academy of Sciences · 1995 · 821 citations

, , +17

Conformation of the Bax C‐terminus regulates subcellular location and cell death

Amotz Nechushtan, Carolyn L. Smith, Yi‐Te Hsu et al. · The EMBO Journal · 1999 · 731 citations · Full text

, , +16

BAX activation is initiated at a novel interaction site

Evripidis Gavathiotis, Motoshi Suzuki, Marguerite L. Davis et al. · Nature · 2008 · 690 citations · Full text

, , +6

1–5 of 387

Authors

1.9K

  1. BA
    Bruno Antonsson

    Merck Serono S.A. (Switzerland), Switzerland

    21 publications · 3.8K citations

    19

    h-index

  2. DW
    David W. Andrews

    McMaster University, Canada

    16 publications · 2.4K citations

    16

    h-index

  3. JM
    Jean‐Claude Martinou

    University of Geneva, Switzerland

    14 publications · 3.7K citations

    14

    h-index

  4. SM
    Sylvie Montessuit

    University of Geneva, Switzerland

    13 publications · 2.6K citations

    13

    h-index

  5. BL
    Brian Leber

    McMaster University, Canada

    12 publications · 2.1K citations

    12

    h-index

1–5 of 1.9K

Institutions

564

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    19 h-index

    54 publications

    16.3K citations

  2. McMaster University

    Hamilton, Canada

    17 h-index

    66 publications

    11.5K citations

  3. Harvard University

    Cambridge, United States

    15 h-index

    60 publications

    11.8K citations

  4. National Institutes of Health

    Bethesda, United States

    14 h-index

    44 publications

    14K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    14 h-index

    52 publications

    3.2K citations

  6. Walter and Eliza Hall Institute of Medical Research

    Melbourne, Australia

    13 h-index

    85 publications

    12.3K citations

  7. Inserm

    Paris, France

    13 h-index

    74 publications

    10.5K citations

  8. Dana-Farber Cancer Institute

    Boston, United States

    12 h-index

    57 publications

    10.8K citations

1–8 of 564

Venues

  1. Journal of Biological Chemistry

    JBC · 45 publications · 6.2K citations

    39

    h-index

  2. Cell Death and Differentiation

    CDD · 28 publications · 2.4K citations

    25

    h-index

  3. Molecular Cell

    14 publications · 2.4K citations

    14

    h-index

  4. The EMBO Journal

    13 publications · 3.9K citations

    13

    h-index

  5. Biochemical and Biophysical Research Communications

    BBRC · 14 publications · 507 citations

    13

    h-index

1–5