Role of PHD fingers and COOH-terminal 30 amino acids in AIRE transactivation activity

Projection of an Immunological Self Shadow Within the Thymus by the Aire Protein

Mark S. Anderson, Emily S. Venanzi, Ludger Klein et al. · Science · 2002 · 2.5K citations

Life Sciences, Genetics, Immunology +17

Clinical Variation of Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy (APECED) in a Series of 68 Patients

Pekka Ahonen, S Myllärniemi, Ilkka Sipilä et al. · New England Journal of Medicine · 1990 · 1.1K citations · Full text

Life Sciences, Clinical Sciences, Dermatology +14

Aire regulates negative selection of organ-specific T cells

Adrian Liston, Sylvie Lesage, Judith Wilson et al. · Nature Immunology · 2003 · 791 citations

Life Sciences, Immunology, Molecular Biology +14

Mutations in the AIRE Gene: Effects on Subcellular Location and Transactivation Function of the Autoimmune Polyendocrinopathy-Candidiasis–Ectodermal Dystrophy Protein

Petra Björses, Maria Halonen, Jorma J. Palvimo et al. · The American Journal of Human Genetics · 2000 · 361 citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

The LxxLL motif: a multifunctional binding sequence in transcriptional regulation

Michael J. Plevin, Morgon M. Mills, Mitsuhiko Ikura · Trends in Biochemical Sciences · 2004 · 255 citations

Medicine, Molecular Biology, Molecular Genetics +16