Concepedia

Enantioselective 1,6-Conjugate Addition to Cyclic Dienones Catalyzed by the Cu−DiPPAM Complex

Joanna Wencel‐Delord, Alexandre Alexakis, Christophe Crévisy, Marc Mauduit

Organic Letters · 2010 · 60 citations · 21 references

DOI

Abstract

In the presence of a Cu/DiPPAM catalytic system, various diorganozinc reagents realize 1,6-asymmetric conjugate addition on various cyclic five- and six-membered cyclic dienones, with complete regioselectivity and high ee's (93-99%).

References

21

Enantioselective Conjugate Silyl Additions to Cyclic and Acyclic Unsaturated Carbonyls Catalyzed by Cu Complexes of Chiral N-Heterocyclic Carbenes

Kang-Sang Lee, Amir H. Hoveyda · Journal of the American Chemical Society · 2010 · 300 citations · Full text

Modular Peptide-Based Phosphine Ligands in Asymmetric Catalysis:  Efficient and Enantioselective Cu-Catalyzed Conjugate Additions to Five-, Six-, and Seven-Membered Cyclic Enones

Sylvia J. Degrado, Hirotake Mizutani, Amir H. Hoveyda · Journal of the American Chemical Society · 2001 · 249 citations

, , +12

Regiodivergent 1,4 versus 1,6 Asymmetric Copper‐Catalyzed Conjugate Addition

Hélène Henon, Marc Mauduit, Alexandre Alexakis · Angewandte Chemie International Edition · 2008 · 180 citations

Preparation of Functionalized Dialkylzincs via a Boron−Zinc Exchange. Reactivity and Catalytic Asymmetric Addition to Aldehydes

Falk Langer, Lothar Schwink, Arokiasamy Devasagayaraj et al. · The Journal of Organic Chemistry · 1996 · 167 citations

, , +15

Catalytic Enantioselective 1,6‐Conjugate Addition of Grignard Reagents to Linear Dienoates

Tim den Hartog, Syuzanna R. Harutyunyan, D. Font et al. · Angewandte Chemie International Edition · 2007 · 140 citations

, , +14